Ready-to-use multiplex immunofluorescence panel

Product Description

Case Analysis

Results Display

Sample Submission Guidelines

Q&A

Product introduction

This product is used for tumor immune microenvironment assessment and clinical development and translational research of tumor immune drugs, covering multiple dimensions such as tumor immunotherapy targets and tumor immune cells. Through high specificity multiplex fluorescence staining, spectral imaging and high throughput image analysis technologies, we can accurately capture tumor microenvironment data to empower anti-tumor drug development.

 

 

Sample image of product BB02

 

 

Service products and cycle

Product Number    

Indicators Tissue Phenotype

Data Analysis

Lead time

BB01

CD3、CD20、CD68、
CD163、Ki67、pan-CK、DAPI

T cells, B cells, M1 macrophages, M2 macrophages

Standard analysis.

1. tissue partitioning: tumor and interstitial.

2. cell typing: defining the different cell types separately and calculating the number, density and percentage of cells.

Extended analysis.

1. Evaluation of expression indicators TPS and CPS;

2  statistics on the number, density, and percentage of immune checkpoint molecules expressed in different types of cells.

3. spatial analysis.

 

10 working days

BB02

CD4、CD8、FOXP3、
PD-1、PD-L1、pan-CK、DAPI

Helper T cells, killer T cells

BB03

CD8、CD68、CD56、
PD-1、PD-L1、pan-CK、DAPI

Treg, immune checkpoint

killer T cells, total macrophages,

Depleted T cells, NK cells, immune checkpoints

BB04

PD-1、PD-L1、CD68、
CD8、CD163、pan-CK、DAPI

M1 macrophages, M2 macrophages, killer T cells, immune checkpoints

BB05

CD3、CD4、CD20、
CD56、FOXP3、pan-CK、DAPI

depleted T cells, immune checkpoints

total T cells, helper T cells.

B cells, NK cells, Treg

BB06

CD4、CD8、GZMB、
Ki67、FOXP3、pan-CK、DAPI

depleted T cells, immune checkpoints

total T cells, helper T cells.

B cells, NK cells, Treg

BB07

CD11c、CD20、CD68、
CD163、CD3、pan-CK、DAPI

tertiary lymphoid structures, B cells, T cells, and

Germinal center activated B cells, follicular dendritic cells

Tertiary lymphoid structures, B cells, killer T cells

BB08

CD20、CD21、CD23、
CD3、Ki67、pan-CK、DAPI

tertiary lymphoid structures, B cells, T cells, and

Germinal center activated B cells, follicular dendritic cells

BB09

CD20、CD23、CD8、
PD-1、PD-L1、pan-CK、DAPI

Tertiary lymphoid structures, B cells, killer T cells

follicular dendritic cells, depleted T cells, immune checkpoints

BB10

PD-1、CD8、CD68、
CD56、FOXP3、pan-CK、DAPI

killer T cells, total macrophages,

NK cells, Treg, immune checkpoints