Single Cell Multiome ATAC + Gene Expression
Single Cell Multiome ATAC + Gene Expression combines ATAC with transcriptome sequencing to identify complex cell populations through integrated analysis of epigenomic and gene expression profiles and detect cellular heterogeneity to uncover hidden information. Combining the discovery of regulatory elements with gene expression could help to explore the gene regulatory interactions that drive cell differentiation, development and disease.
Sample types: animal tissues, single cell suspensions, nuclear suspensions, cell lines.
Experimental process
Flow Chart of ATAC+Gene Expression Experiment in Single Cell Multiomics
Analysis process
Flow Chart of ATAC+Gene Expression Analysis in Single Cell Multiomics
Application directions
a. Biomarker discovery;
b. Cell lineage and developmental program tracking;
c. Cell heterogeneity and detection of rare cell populations;
d. Gene regulatory networks;
e. Response to therapeutic interventions.
Product advantages
a. Efficiently distributing 500-10,000 nuclei per lane, analyzing up to 80,000 nuclei per run ;
b. Extensible to run up to 8 samples in parallel;
c. Nuclei recovery up to 65%;
d. High sensitivity;
e. Low microfluidic double rate (less than 1% per 1,000 nuclei);
f. Suitable for studies with cell lines, primary cells, fresh and frozen samples.